KMID : 0363220170550020124
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Korean Journal of Dermatology 2017 Volume.55 No. 2 p.124 ~ p.128
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A Case of Malignancy-associated Histiocytoid Sweet Syndrome in a Patient with AML
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Seo Jeong-Wan
Kim Tae-Hoon Choi Seung-Hwan Ha Seung-Min Song Ki-Hoon Kim Ki-Ho
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Abstract
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Sweet syndrome is a disorder characterized by painful, erythematous, cutaneous plaques and nodules of rapid onset accompanied by fever, leukocytosis, and neutrophilia. We encountered a case of a recurrent histiocytoid Sweet syndrome in a patient with acute myeloid leukemia (AML). A 64-year-old Korean man was diagnosed with complete remission of AML and had symptomatic nodules and plaques on the dorsal sides of both hands. Approximately 3 years prior, he also had symptomatic plaques at the same site and had been diagnosed with MDS (Myelodysplastic syndrome). We performed a biopsy and diagnosed this case as a malignancy-associated histiocytoid Sweet syndrome. Most Sweet syndrome cases are acute; in contrast, this case was chronic with a relapse. In addition, histopathologic examination showed a dense histiocytic infiltration. These histiocytoid cells are usually misinterpreted as histiocytes; however, they are actually immature myeloid cells. Herein, we report a case of a recurrent malignancy-associated histiocytoid Sweet syndrome in a patient with a hematologic disorder.
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KEYWORD
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Malignancy-associated Sweet syndrome, Histiocytoid Sweet syndrome, AML
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